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Answers from vets about your cat:

Why Does My Vet Want a Urine Sample from My Cat?

Reviewed by Dr. Celeste Clements, DVM, DACVIM on Wednesday, May 27, 2015
Posted April 28, 2015 in Cat Checkups & Preventive Care

Cat on kitchen floor

Chances are that the last time you went to your physician for a physical examination, your health care provider handed you a sample cup and pointed to the restroom so you could “pee in the cup.” This procedure has become so normal that we probably prepare by not urinating in anticipation. That is because analyzing a urine sample (doing a urinalysis) is a relatively quick and easy way to get a lot of valuable information.

Your veterinarian likely recommends running a urinalysis, not only on your cat when she is sick, but also sometimes when she seems perfectly healthy. In fact, years ago my friend, Dr. Carl Osborne, a veterinarian renowned for his interest in urinary disorders, told me that, as far as he was concerned, no physical examination was complete without a urinalysis.

What can a urinalysis tell your veterinarian about your cat?
Your veterinarian will look at the following aspects of the urine sample:

  • Color and Appearance-- Is it yellow and clear/transparent as it should be or is it cloudy, dark or bloody indicating something abnormal is suspended in it (such as blood cells, cancer cells, crystals, mucus, bacteria and remnants of damaged kidney cells or casts).
  • Microscopic Appearance-- When evaluated under a microscope, a drop of urine can confirm the presence of those suspended components mentioned above.
  • Specific Gravity-- This is a test that determines the concentration of the urine as a number on a scale with 1.000 being the standard, based on distilled water, and the values increasing from there. The specific gravity reading of one single urine sample is not entirely diagnostic because urine concentration varies with hydration status and water consumption. But the value can lead your veterinarian to pursue other tests.
  • Chemical tests-- There are many very sophisticated chemical tests that can also be performed on a urine sample, but in a routine urinalysis some of the things your veterinarian will check for are:
    • Glucose (sugar)-- Can indicate diabetes mellitus, kidney disease or other genetic disorders.
    • Protein in increased amounts-- Can result from infection, inflammation, hemorrhage, or other metabolic diseases.
    • Bilirubin or bile pigments in increased numbers-- Can indicate liver disease or red blood cell destruction.
    • Blood-- Either whole cells or just pigment from active bleeding and/or red blood cell destruction may signal infection.
    • pH or the acidity changes of the urine-- Can indicate kidney disease or infection.
    • Ketones-- By-products of protein metabolism; their presence can indicate starvation (either literal or due to metabolic disease like diabetes mellitus)

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Mike has more than 35 years of experience in companion animal veterinary practice and is a valued member of IDEXX’s Pet Health Network team since 2013.